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. 2022 Aug 17;12:13913. doi: 10.1038/s41598-022-17791-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The frequency and distribution of RET alterations in TCGA cancers. (A) The frequency of combined RET alterations including mutations and CNVs among 32 TCGA cancers. (B) The distribution of RET CNVs in combination with RET mutations in diverse RET functional domains.