TABLE 4.
Subgroup analysis of the associations of sleep duration and sleep-onset latency time with total CVD.
| Sleep duration OR (95% CI) P |
Sleep-onset latency time OR (95% CI) P |
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| <7 vs. 7–8 h | P for interaction | >8 vs. 7–8 h | P for interaction | <5 vs. 5–30 min | P for interaction | >30 vs. 5–30 min | P for interaction | |
| Age | 0.441 | 0.379 | 0.455 | 0.170 | ||||
| <60 year | 1.56 (1.09, 2.22) *P = 0.044 |
1.02 (0.50, 2.11) P = 0.949 |
0.68 (0.38, 1.21) P = 0.229 |
1.77 (1.21, 2.60) *P = 0.022 |
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| ≥60 year | 1.38 (0.93, 2.04) P = 0.095 |
1.70 (0.92, 3.14) P = 0.080 |
0.88 (0.60, 1.29) P = 0.524 |
1.28 (0.83, 1.97) P = 0.295 |
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| Gender | 0.249 | 0.432 | *0.049 | 0.578 | ||||
| Male | 1.29 (0.99, 1.68) P = 0.107 |
1.21 (0.80, 1.85) P = 0.397 |
0.98 (0.69, 1.41) P = 0.926 |
1.87 (1.30, 2.68) *P = 0.011 |
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| Female | 1.55 (0.98, 2.45) P = 0.057 |
1.64 (0.92, 2.94) P = 0.139 |
0.52 (0.33, 0.81) *P = 0.023 |
1.33 (0.89, 2.00) P = 0.207 |
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| Obesity | 0.932 | 0.787 | 0.725 | 0.487 | ||||
| BMI ≥ 30 | 1.35 (0.97, 1.88) P = 0.116 |
1.43 (0.80, 2.56) P = 0.263 |
0.81 (0.55, 1.18) P = 0.304 |
1.37 (0.85, 2.20) P = 0.234 |
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| BMI < 30 | 1.46 (0.93, 2.28) P = 0.086 |
1.46 (0.84, 2.55) P = 0.220 |
0.73 (0.51, 1.06) P = 0.139 |
1.73 (1.27, 2.37) *P = 0.011 |
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| Abdominal obesity | 0.252 | 0.381 | 0.660 | 0.454 | ||||
| Yes | 1.52 (1.19, 1.95) *P = 0.016 |
1.65 (0.92, 2.95) P = 0.079 |
0.74 (0.53, 1.03) P = 0.128 |
1.46 (0.98, 2.18) P = 0.114 |
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| No | 1.17 (0.75, 1.84) P = 0.508 |
1.04 (0.54, 2.01) P = 0.913 |
0.83 (0.56, 1.24) P = 0.398 |
1.98 (1.32, 2.99) *P = 0.014 |
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| Diabetes | 0.455 | 0.695 | 0.537 | 0.745 | ||||
| Yes | 1.13 (0.74, 1.73) P = 0.580 |
1.27 (0.63, 2.56) P = 0.523 |
0.90 (0.56, 1.44) P = 0.665 |
1.41 (0.73, 2.73) P = 0.337 |
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| No | 1.51 (1.13, 2.01) *P = 0.025 |
1.44 (0.84, 2.45) P = 0.220 |
0.73 (0.51, 1.05) P = 0.127 |
1.62 (1.22, 2.16) *P = 0.010 |
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| Hypertension | 0.574 | 0.699 | 0.210 | 0.363 | ||||
| Yes | 1.33 (0.96, 1.85) P = 0.074 |
1.47 (0.93, 2.34) P = 0.147 |
0.84 (0.62, 1.15) P = 0.316 |
1.42 (0.98, 2.06) P = 0.105 |
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| No | 1.64 (0.93, 2.90) P = 0.080 |
1.25 (0.64, 2.47) P = 0.536 |
0.57 (0.32, 1.03) P = 0.060 |
2.33 (1.45, 3.74) *P = 0.010 |
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| Physical activity | 0.509 | 0.139 | 0.277 | 0.436 | ||||
| Active | 1.43 (0.98, 2.08) P = 0.060 |
0.86 (0.42, 1.77) P = 0.695 |
0.80 (0.52, 1.21) P = 0.320 |
1.99 (1.35, 2.93) **P = 0.008 |
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| Inactive | 1.48 (1.08, 2.02) *P = 0.042 |
1.95 (1.15, 3.31) *P = 0.038 |
0.70 (0.53, 0.93) *P = 0.038 |
1.31 (0.90, 1.89) P = 0.192 |
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OR, odds ratio; CI, confidence interval. Analyses were adjusted for sex, age, race, education, smoking status, alcohol consumption status, PIR, BMI, diabetes, hypertension, activity, TC, HDL-C, and TG when they were not the strata variables. The results are weighted based on the survey. *P < 0.05; **P < 0.01.