TABLE 5.
Subgroup analysis of the associations of sleep-related disorders with total CVD.
| Sleep problems OR (95% CI) P |
P for interaction | OSA symptoms OR (95% CI) P |
P for interaction | Daytime sleepiness OR (95 %CI) P |
P for interaction | |
| Age | *0.019 | 0.361 | 0.273 | |||
| <60 year | 2.74 (1.74, 4.32) **P = 0.003 |
1.19 (0.79, 1.79) P = 0.437 |
1.54 (1.09, 2.17) *P = 0.039 |
|||
| ≥60 year | 1.29 (1.14, 1.68) *P = 0.037 |
1.04 (0.84, 1.28) P = 0.736 |
1.36 (1.14, 1.62) **P = 0.009 |
|||
| Gender | 0.841 | 0.519 | 0.351 | |||
| Male | 1.77 (1.38, 2.27) **P = 0.002 |
1.04 (0.77, 1.41) P = 0.808 |
1.19 (0.89, 1.60) P = 0.268 |
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| Female | 1.72 (1.21, 2.43) *P = 0.016 |
1.19 (0.84, 1.68) P = 0.364 |
1.85 (1.36, 2.53) **P = 0.004 |
|||
| Obesity | 0.692 | 0.997 | 0.226 | |||
| BMI ≥ 30 | 1.82 (1.36, 2.43) **P = 0.004 |
1.10 (0.73, 1.66) P = 0.653 |
1.24 (0.91, 1.68) P = 0.203 |
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| BMI < 30 | 1.63 (1.17, 2.26) *P = 0.020 |
1.13 (0.92, 1.40) P = 0.275 |
1.75 (1.29, 2.37) **P = 0.007 |
|||
| Abdominal obesity | 0.622 | 0.715 | 0.384 | |||
| Yes | 1.76 (1.40, 2.22) **P = 0.002 |
1.05 (0.76, 1.46) P = 0.769 |
1.41 (1.13, 1.77) *P = 0.020 |
|||
| No | 1.61 (0.97, 2.69) P = 0.063 |
1.30 (0.93, 1.82) P = 0.169 |
1.97 (1.23, 3.15) *P = 0.022 |
|||
| Diabetes | 0.801 | 0.373 | 0.899 | |||
| Yes | 1.67 (1.21, 2.32) *P = 0.015 |
0.97 (0.64, 1.45) P = 0.880 |
1.39 (0.97, 1.97) P = 0.107 |
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| No | 1.74 (1.34, 2.27) **P = 0.003 |
1.21 (0.95, 1.54) P = 0.150 |
1.53 (1.19, 1.98) **P = 0.009 |
|||
| Hypertension | 0.560 | 0.944 | 0.285 | |||
| Yes | 1.83 (1.41, 2.36) **P = 0.002 |
1.12 (0.88, 1.42) P = 0.391 |
1.42 (1.17, 1.73) **P = 0.008 |
|||
| No | 1.44 (0.87, 2.38) P = 0.189 |
1.04 (0.58, 1.87) P = 0.905 |
1.99 (1.25, 3.16) *P = 0.019 |
|||
| Physical activity | 0.230 | 0.341 | 0.771 | |||
| Active | 1.59 (1.08, 2.32) *P = 0.042 |
1.27 (0.87, 1.84) P = 0.250 |
1.67 (1.23, 2.26) **P = 0.009 |
|||
| Inactive | 1.93 (1.50, 2.48) ***P < 0.001 |
0.98 (0.78, 1.23) P = 0.859 |
1.46 (1.14, 1.87) *P = 0.016 |
OR, odds ratio; CI, confidence interval. Analyses were adjusted for sex, age, race, education, smoking status, alcohol consumption status, PIR, BMI, diabetes, hypertension, activity, TC, HDL-C, and TG when they were not the strata variables. The results are weighted based on the survey. *P < 0.05; **P < 0.01; ***P < 0.001.