Table 2.
Tumor characteristics and laboratory values
| Age < 70 (n = 1056) | Age 70 + (n = 477) | P value | |
|---|---|---|---|
| Tumor size, mean (SD), cm | 5.6 (4.4) | 6.2 (4.3) | P < .001 |
| Bilateral, no. (%) | 134 (14.7) | 57 (13.3) | P = .51 |
| Single tumor, no. (%) | 690 (67.2) | 350 (73.8) | P = .009 |
| Met Milan criteria, no. (%) | 462 (43.8) | 178 (37.4) | P = .02 |
| Normal AFP, no. (%) | 414 (39.4) | 212 (45.0) | P = .04 |
| AFP, mean (SD), ng/mL | 11,980 (54576) | 9743 (60365) | P = .006 |
| Cirrhosis, no. (%) | 774 (74.4) | 303 (64.6) | P < .001 |
| Rupture, no. (%) | 40 (3.8) | 18 (3.8) | P = .99 |
| APRI, mean (SD) | 0.79 (0.84) | 0.45 (0.64) | P < .001 |
| MELD, mean (SD) | 10.5 (4.5) | 10.2 (4.09) | P = .56 |
| Childs–Turcotte–Pugh Score, mean (SD) | 6.5 (2.0) | 5.9 (1.4) | P < .001 |
| Bilirubin, mean (SD), mg/dL | 1.7 (2.7) | 1.2 (1.7) | P < .001 |
| Albumin, mean (SD), g/dL | 3.52 (0.74) | 3.71 (0.63) | P < .001 |
| Prothrombin time, mean (SD), s | 14.6 (2.4) | 14.1 (2.0) | P < .001 |
| INR, mean (SD) | 1.18 (0.27) | 1.13 (0.23) | P < .001 |
| Platelets, mean (SD), 103/μL | 161.3 (95.8) | 183.0 (92.5) | P < .001 |
| Creatinine, mean (SD), mg/dL | 0.98 (0.71) | 1.18 (0.93) | P < .001 |
| AST, mean (SD), IU/L | 91.5 (84.8) | 61.8 (54.2) | P < .001 |
| ALT, mean (SD), IU/L | 67.0 (60.5) | 50.6 (45.2) | P < .001 |