TABLE 4.
Univariable and multivariable binary logistic regression analysis to evaluate associations of NEWS and MEWS scores to predict mortality, readmission, discharge type, and time to readmission.
| Variables | Univariate | Multivariate | ||
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| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Mortality (Yes vs. No) | ||||
| Age | 1.01 (0.97–1.03) | 0.741 | – | – |
| Gender (Male vs. Female) | 1.17 (0.57–2.426) | 0.66 | – | – |
| Comorbidities (Yes vs. No) | 2.90 (1.33–6.29) | 0.007* | 3.23 (0.82–12.6) | 0.092 |
| Comorbidities (≥2 vs. 1) | 5.60 (2.14–14.66) | <0.001* | 2.19 (0.37–12.8) | 0.385 |
| SOFA | 2.05 (1.67–2.52) | <0.001* | 0.64 (0.23–1.74) | 0.385 |
| APACHE IV | 1.48 (1.32–1.65) | <0.001* | 1.50 (0.87–2.58) | 0.137 |
| NEWS score | 18.58 (8.45–40.86) | <0.001* | 6.51 (1.81–23.4) | 0.004* |
| MEWS score | 12.19 (6.43–23.12) | <0.001* | 2.62 (0.86–7.95) | 0.089 |
| ICU Readmission (Yes vs. No) | ||||
| Age | 1.01 (0.98–1.03) | 0.382 | – | – |
| Gender (Male vs. Female) | 2.17 (1.18–3.97) | 0.012* | 2.36 (1.18–4.70) | 0.015* |
| Comorbidities (Yes vs. No) | 1.50 (0.82–2.71) | 0.18 | – | – |
| Comorbidities (≥2 vs. 1) | 1.88 (0.67–5.28) | 0.225 | – | – |
| SOFA | 1.30 (1.13–1.49) | <0.001* | 1.02 (0.54–1.93) | 0.935 |
| APACHE IV | 1.14 (1.06–1.22) | <0.001* | 0.95 (0.68–1.33) | 0.798 |
| NEWS score | 2.17 (1.52–3.10) | <0.001* | 2.24 (1.11–5.54) | <0.001* |
| MEWS score | 3.43 (2.36–4.99) | <0.001* | 8.12 (3.71–17.80) | <0.001* |
| Discharge type (Unplanned vs. Planned) | ||||
| Age | 0.93 (0.91–0.97) | 0.001* | 0.93 (0.90–0.97) | 0.002* |
| Gender (Male vs. Female) | 1.05 (0.41–2.73) | 0.911 | – | – |
| Comorbidities (Yes vs. No) | 0.76 (0.29–2.01) | 0.588 | – | – |
| Comorbidities (≥2 vs. 1) | 0.87 (0.35–3.54) | 0.998 | – | – |
| SOFA | 0.66 (0.49–0.88) | 0.006* | 0.67 (0.27–1.65) | 0.392 |
| APACHE IV | 0.82 (0.71–0.96) | 0.013* | 1.03 (0.64–1.65) | 0.884 |
| NEWS score | 0.67 (0.32–1.41) | 0.299 | – | – |
| MEWS score | 1.16 (0.65–2.09) | 0.604 | – | – |
| Time to readmission (< 4 days vs. ≥4 days) | ||||
| Age | 1.01 (0.97–1.03) | 0.862 | – | – |
| Gender (Male vs. Female) | 1.62 (0.82–3.19) | 0.164 | – | – |
| Comorbidities (Yes vs. No) | 1.03 (0.52–2.04) | 0.916 | – | – |
| Comorbidities (≥2 vs. 1) | 0.87 (0.19–3.84) | 0.854 | – | – |
| SOFA | 1.32 (1.14–1.54) | <0.001* | 1.15 (0.58–2.27) | 0.672 |
| APACHE IV | 1.15 (1.06–1.25) | <0.001* | 0.93 (0.65–1.33) | 0.709 |
| NEWS score | 1.87 (1.26–2.78) | 0.002* | 3.21 (1.08–6.51) | 0.001* |
| MEWS score | 2.84 (1.94–4.17) | <0.001* | 7.04 (2.95–16.77) | <0.001* |
*P-value < 0.05 considered significant, Abbreviations: Odds ratio (OR), Confidence Interval (CI), Acute Physiology and Chronic Health Evaluation IV (APACHE-IV), Sequential Organ Failure Assessment (SOFA), National Early Warning Score (NEWS), Modified Early Warning Score (MEWS).