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. 2022 Aug 4;9:938005. doi: 10.3389/fmed.2022.938005

TABLE 5.

Univariable and multivariable binary logistic regression analysis to evaluate associations of NEWS and MEWS scores to predict MV status, MV duration, and organ failure after readmission.

Variables Univariate Multivariate


OR (95% CI) P-value OR (95% CI) P-value
MV after Readmission (Yes vs. No)
Age 1.01 (0.98–1.03) 0.493
Gender (Male vs. Female) 2.02 (1.03–3.96) 0.039
Comorbidities (Yes vs. No) 1.47 (0.76–2.85) 0.252
Comorbidities (≥2 vs. 1) 2.58 (0.91–7.31) 0.074
SOFA 1.32 (1.14–1.54) <0.001* 0.98 (0.51–1.90) 0.967
APACHE IV 1.16 (1.07–1.25) <0.001* 0.98 (0.69–1.38) 0.917
NEWS score 2.28 (1.55–3.35) <0.001* 1.35 (1.10–4.78) 0.011*
MEWS score 3.15 (2.15–4.64) <0.001* 5.38 (2.42–11.96) <0.001*
MVduration after readmission (≥6 days vs. <6 days)
Age 1.00 (0.97–1.04) 0.771
Gender (Male vs. Female) 2.98 (1.19–7.49) 0.020* 3.01 (1.14–7.95) 0.026*
Comorbidities (Yes vs. No) 1.23 (0.52–2.90) 0.637
Comorbidities (≥2 vs. 1) 2.62 (0.72–9.55) 0.143
SOFA 1.25 (1.03–1.51) 0.020* 0.67 (0.29–1.53) 0.350
APACHE IV 1.12 (1.02–1.24) 0.016* 1.25 (0.81–1.95) 0.313
NEWS score 1.90 (1.17–3.08) 0.009* 2.18 (1.10–4.78) 0.011*
MEWS score 2.92 (1.87–4.56) <0.001* 12.39 (3.36–45.67) <0.001*
Multiple organ failure after readmission (Yes vs. No)
Age 1.01 (0.98–0.03) 0.485
Gender (Male vs. Female) 2.43 (1.31–4.53) 0.0058 2.67 (1.32–5.40) 0.006*
Comorbidities (Yes vs. No) 1.37 (0.75–2.51) 0.304
Comorbidities (≥2 vs. 1) 1.98 (0.71–5.57) 0.191
SOFA 1.29 (1.12–1.48) <0.001* 1.09 (0.57–2.06) 0.784
APACHE IV 1.13 (1.05–1.22) <0.001* 0.91 (0.65–1.27) 0.594
NEWS score 2.17 (1.51–3.11) <0.001* 3.27 (1.12–8.59) 0.001*
MEWS score 3.33 (2.29–4.84) <0.001* 7.44 (3.39–16.36) <0.001*

*P-value < 0.05 considered significant. Odds ratio (OR), Confidence Interval (CI), Acute Physiology and Chronic Health Evaluation IV (APACHE-IV), Sequential Organ Failure Assessment (SOFA), National Early Warning Score (NEWS), Modified Early Warning Score (MEWS).