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. 2022 Aug 16;219(10):e20220780. doi: 10.1084/jem.20220780

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© 2022 Lim et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 1. — Phenotypic analysis of T cells in nasal secretion. (A) Schematic of experimental design. (B) Frequency of tissue-resident T cells present in PBMCs (n = 8) and nasal secretion (n = 10). Convalescent vaccinees are indicated by a triangle symbol. (C) Frequency of CD4 and CD8 T cells present in PBMCs (n = 14) or nasal cells (n = 10). Convalescent vaccinees are indicated by a triangle. (D) Proportion of naive (CCR7⁺CD45RA⁺), central (CCR7⁺CD45RA⁻; TCM), effector (CCR7⁻CD45RA⁻; TEM) and terminally differentiated (CCR7⁻CD45RA⁺; TEMRA) memory CD4⁺ and CD8⁺ nasal T cells (n = 10). (E) Proportion of tissue-resident marker (CD69 and CD103) expression on CD8 and CD4 nasal T cells (n = 10) and corresponding representative plots.