Table 1. Basic clinical characteristics of all participants.
Characteristics | AML group | Control group |
---|---|---|
Age/years, median (range) | 47.5 (14–86) | 38.5 (24–72) |
Age group/n (%) | ||
≥60 years | 30 (23.4) | 6 (37.5) |
<60 years | 98 (76.6) | 10 (62.5) |
Gender/n (%) | ||
Men | 73 (57.8) | 9 (56,2) |
Women | 55 (42.2) | 7 (43.8) |
FAB subtypes/n (%) | ||
M0 | 4 (3.1) | |
M1 | 6 (4.7) | |
M2 | 68 (53.1) | |
M4 | 15 (11.7) | |
M5 | 33 (25.8) | |
M6 | 1 (0.8) | |
M7 | 1(0.8) | |
Prognosis Risk/n (%) | ||
Good | 20 (15.7) | |
Intermediate | 59(46) | |
Poor | 49 (38.3) | |
Cytogenetics/n (%) | ||
Normal | 63 (49.2) | |
Complex | 10 (7.8) | |
inv(16) or t(16;16)/CBFβ/MYH11 | 5 (3.9) | |
t(8;21)/AML1/ETO | 21 (16.4) | |
11q23/MLL | 8 (6.2) | |
t(9;22)/BCR/ABL1 | 3 (2.4) | |
Others | 18 (14.1) | |
Molecular genetics/n (%) | ||
FLT3-ITD | 23 (17.9) | |
c-Kit | 14 (10.9) | |
NPM-1 | 20 (15.6) | |
TP53 | 2 (1.5) | |
RUNX1 | 3 (2.3) | |
ASXL1 | 7 (5.5) | |
DNMT3a | 7 (5.5) | |
SF3B1 | 1 (0.8) | |
CEBPA double mutation | 7 (5.5) | |
IDH1 | 8 (6.3) | |
IDH2 | 8 (6.3) |