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. 2022 Aug 18;12:14050. doi: 10.1038/s41598-022-18367-6

Figure 1.

Figure 1

Antiviral efficacy of CPC against SARS-CoV-2 by plaque assay using Vero E6 cells expressing the TMPRSS2 gene (VeroE6/TMPRSS2). The virus titers were counted and the virus titer of SARS-CoV-2 Wuhan (a), Alpha (b), Beta (c) and Gamma (d) strains treated by CPC (0–40 μg/mL) at room temperature for 30 min were quantified and represented as PFU/mL. Plaque assay was also performed in the presence of PBS, CPC (50 μg/mL) or Triton X-100 (1%) for 10 min. Thereafter, samples were filtered by PD-10 columns to eliminate reagents (e). Statistical analysis was performed using one-way analysis of variance. (*p < 0.05).