Table 5. Pearson correlation factors between conventional 2D and dose-volume parameters by type of surgery and treatment technique .
| Variable | BCS PCF (P-value) |
MRM PCF (P-value) |
2FRT PCF (P-value) |
3FRT PCF (P-value) |
| CLD vs. DVH (ipsilateral lung) | ||||
| V5Gy (%) | 0.501 (< 0.001) | 0.530 (< 0.001) | 0.151 (0.346) | 0.688 (< 0.001) |
| V10Gy (%) | 0.578 (< 0.001) | 0.572 (< 0.001) | 0.316 (0.044) | 0.698 (< 0.001) |
| V20Gy (%) | 0.637 (< 0.001) | 0.617 (< 0.001) | 0.453 (0.003) | 0.732 (< 0.001) |
| Dmean (Gy) | 0.314 (0.013) | 0.414 (0.001) | 0.105 (0.514) | 0.559 (< 0.001) |
| MLD vs. DVH (ipsilateral lung) | ||||
| V5Gy (%) | 0.478 (< 0.001) | 0.518 (< 0.001) | 0.330 (0.035) | 0.650 (< 0.001) |
| V10Gy (%) | 0.515 (< 0.001) | 0.569 (< 0.001) | 0.463 (0.002) | 0.628 (< 0.001) |
| V20Gy (%) | 0.610 (< 0.001) | 0.628 (< 0.001) | 0.593 (< 0.001) | 0.692 (< 0.001) |
| Dmean (Gy) | 0.623 (< 0.001) | 0.572 (< 0.001) | 0.425 (0.006) | 0.704 (< 0.001) |
| MHL vs. DVH (heart) | ||||
| V5Gy (%) | 0.319 (0.080) | 0.215 (0.246) | 0.264 (0.262) | 0.317 (0.041) |
| V10Gy (%) | 0.274 (0.136) | 0.248 (0.179) | 0.264 (0.261) | 0.324 (0.037) |
| V20Gy (%) | 0.280 (0.126) | 0.298 (0.103) | 0.378 (0.101) | 0.297 (0.056) |
| V25Gy (%) | 0.389 (0.031) | 0.336 (0.065) | 0.407 (0.075) | 0.409 (0.007) |
| Dmean (Gy) | 0.353 (0.052) | 0.303 (0.097) | 0.333 (0.152) | 0.381 (0.013) |
| MHD vs. DVH (heart) | ||||
| V5Gy (%) | 0.641 (< 0.001) | 0.790 (< 0.001) | 0.901 (< 0.001) | 0.588 (< 0.001) |
| V10Gy (%) | 0.636 (< 0.001) | 0.769 (< 0.001) | 0.875 (< 0.001) | 0.577 (< 0.001) |
| V20Gy (%) | 0.566 (0.001) | 0.796 (< 0.001) | 0.923 (< 0.001) | 0.521 (< 0.001) |
| V25Gy (%) | 0.665 (< 0.001) | 0.811 (< 0.001) | 0.934 (< 0.001) | 0.600 (< 0.001) |
| Dmean (Gy) | 0.632 (< 0.001) | 0.812 (< 0.001) | 0.910 (< 0.001) | 0.581 (< 0.001) |
| CWS vs. DMax breast | - | - | 0.098 (0.672) | 0.108 (0.502) |
CLD: Central lung depth; DVH: Dose-volume histogram; MLD: Maximum lung depth; MHL: Maximum heart length; MHD: Maximum heart distance; Vx: Volume of lung or heart receiving xGy; Dmean: Mean dose; Dmax: Maximum dose; CWS: Chest wall separation; BCS: Breast conserving surgery; MRM: Modified radical mastectomy; 2FRT: Two-field radiotherapy; 3FRT: Three-field radiotherapy PCF: Pearson correlation factor;PCF significant if P ≤ 0.01; PCF ≥ 0.7: Good correlation; PCF ≥ 0.5 and < 0.7: Moderate correlation; PCF < 0.5: Poor correlation.