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. 2022 Mar 2;36:16. doi: 10.47176/mjiri.36.16

Table 5. Pearson correlation factors between conventional 2D and dose-volume parameters by type of surgery and treatment technique .

Variable BCS
PCF (P-value)
MRM
PCF (P-value)
2FRT
PCF (P-value)
3FRT
PCF (P-value)
CLD vs. DVH (ipsilateral lung)
V5Gy (%) 0.501 (< 0.001) 0.530 (< 0.001) 0.151 (0.346) 0.688 (< 0.001)
V10Gy (%) 0.578 (< 0.001) 0.572 (< 0.001) 0.316 (0.044) 0.698 (< 0.001)
V20Gy (%) 0.637 (< 0.001) 0.617 (< 0.001) 0.453 (0.003) 0.732 (< 0.001)
Dmean (Gy) 0.314 (0.013) 0.414 (0.001) 0.105 (0.514) 0.559 (< 0.001)
MLD vs. DVH (ipsilateral lung)
V5Gy (%) 0.478 (< 0.001) 0.518 (< 0.001) 0.330 (0.035) 0.650 (< 0.001)
V10Gy (%) 0.515 (< 0.001) 0.569 (< 0.001) 0.463 (0.002) 0.628 (< 0.001)
V20Gy (%) 0.610 (< 0.001) 0.628 (< 0.001) 0.593 (< 0.001) 0.692 (< 0.001)
Dmean (Gy) 0.623 (< 0.001) 0.572 (< 0.001) 0.425 (0.006) 0.704 (< 0.001)
MHL vs. DVH (heart)
V5Gy (%) 0.319 (0.080) 0.215 (0.246) 0.264 (0.262) 0.317 (0.041)
V10Gy (%) 0.274 (0.136) 0.248 (0.179) 0.264 (0.261) 0.324 (0.037)
V20Gy (%) 0.280 (0.126) 0.298 (0.103) 0.378 (0.101) 0.297 (0.056)
V25Gy (%) 0.389 (0.031) 0.336 (0.065) 0.407 (0.075) 0.409 (0.007)
Dmean (Gy) 0.353 (0.052) 0.303 (0.097) 0.333 (0.152) 0.381 (0.013)
MHD vs. DVH (heart)
V5Gy (%) 0.641 (< 0.001) 0.790 (< 0.001) 0.901 (< 0.001) 0.588 (< 0.001)
V10Gy (%) 0.636 (< 0.001) 0.769 (< 0.001) 0.875 (< 0.001) 0.577 (< 0.001)
V20Gy (%) 0.566 (0.001) 0.796 (< 0.001) 0.923 (< 0.001) 0.521 (< 0.001)
V25Gy (%) 0.665 (< 0.001) 0.811 (< 0.001) 0.934 (< 0.001) 0.600 (< 0.001)
Dmean (Gy) 0.632 (< 0.001) 0.812 (< 0.001) 0.910 (< 0.001) 0.581 (< 0.001)
CWS vs. DMax breast - - 0.098 (0.672) 0.108 (0.502)

CLD: Central lung depth; DVH: Dose-volume histogram; MLD: Maximum lung depth; MHL: Maximum heart length; MHD: Maximum heart distance; Vx: Volume of lung or heart receiving xGy; Dmean: Mean dose; Dmax: Maximum dose; CWS: Chest wall separation; BCS: Breast conserving surgery; MRM: Modified radical mastectomy; 2FRT: Two-field radiotherapy; 3FRT: Three-field radiotherapy PCF: Pearson correlation factor;PCF significant if P ≤ 0.01; PCF ≥ 0.7: Good correlation; PCF ≥ 0.5 and < 0.7: Moderate correlation; PCF < 0.5: Poor correlation.