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. 2022 Aug 4;7(32):28434–28444. doi: 10.1021/acsomega.2c03127

Table 1. Antibacterial Activity of 8–23 against S. aureus and P. aeruginosa.

compound MSSA MIC (μg/mL)a WTPA MIC (μg/mL)a
8 >128 >256
9 >128 >128
10 >128 >128
11 >128 >128
12 >128 >128
13 >128 >128
14 >128 >128
15 >128 >256
16 >128 >128
17 64 >256
18 >128 >256
19 >128 >256
20 >128 >128
21 >128 >128
22 >128 >256
23 >128 >128
a

n = 3, MIC = minimum inhibitory concentration of >85% reduction in pathogen growth with compound compared to pathogen alone (DMSO only) at OD 590 nm (no visible growth).