Table 2. Antibacterial Activity of 8, 15, 17, 18, 19, and 22 against P. aeruginosa Efflux Knockout PΔ6.

compound	PΔ6 MIC (μg/mL)a
8	64 [>4]
15	>256 [0]
17	256 [>2]
18	>256 [0]
19	>256 [0]
22	>256 [0]

^an = 3, MIC = concentration of compound with no visible pathogen growth compared to pathogen (+vehicle) alone; brackets indicate fold increase compared to WTPA MIC, as shown in Table 1.