Table 7. IC₅₀ of Compounds 178, 179, Actinomycin D, Colchicine, and Gefitinib toward MCF-7, Tubulin, and EGFR.

compound no.	MCF (IC50, μM)	tubulin (IC50, μM)	EGFR (IC50, μM)
178	0.55 ± 0.24	26.5	0.17 ± 0.03
179	3.55 × 10–4 ± 0.07	5.51 × 10–5	0.09 ± 0.03
actinomycin D	37.82 ± 1.30		0.04 ± 0.03
colchicine		9.88 × 10–2
gefitinib			0.03 ± 0.02