Table 1. In Vitro α-Glucosidase Inhibition Activity of the Synthesized Compounds (5–24).

compounds	substituents attached	IC50 ± μM (SEM)
5	4-NO2 C6H4	5.22 ± 0.14
6	4-OH C6H4	N/Aa
7	4-Cl C6H4	N/A
8	4-CHO C6H4	5.69 ± 0.10
9	3,4,5-OCH3C6H2	N/A
10	3-OHC6H4	N/A
11	2-OH,3-OCH3C6H3	24.10 ± 0.30
12	2,4-ClC6H3	33.39 ± 0.38
13	4-N,N(CH2CH3)2C6H4	189.89 ± 0.53
14	4-OH,3-OCH3C6H3	10.20 ± 0.12
15	2-OCH3C6H4	89.28 ± 0.52
16	3-OCH3C6H4	71.64 ± 0.58
17	4-OCH3C6H4	63.68 ± 0.52
18	2-OHC6H4	N/A
19	5-CH3C4H2O	39.06 ± 0.27
20	4-CH(CH3)2C6H4	65 ± 1.55
21	2-C4H2S	54.43 ± 0.65
22	2-C10H7	41.00 ± 0.36
23	4-FC6H4	26.38 ± 0.18
24	4-CH3C6H4	23.75 ± 0.25
acarbose	standard	873 ± 1.2 μM

^aN/A (not active).