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. 2022 Aug 18;24:199. doi: 10.1186/s13075-022-02850-6

Fig. 6.

Fig. 6

Maximal target engagement with daily CC-99677 dosing does not change leukocyte/leukocyte subtype cell counts. Total WBC count (a), lymphocyte count (b), monocyte count (c), and absolute neutrophil count (ANC) (d) are shown at the indicated time points of dosing. (Note: neutropenia defined as ANC < 1.5 × 109/L). All CC-99677 data at 150-mg dose level from pre-dose baseline to last dose on day 14 (n = 5). Total placebo n = 9. Data are mean (SD). SD, standard deviation; WBC, white blood cell