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. 2022 Aug 17;17:52. doi: 10.1186/s13024-022-00554-8

Fig. 1.

Fig. 1

Project design schematic representation and monocytes DEG. a Schematic representation of project design and rationale for the comparison of the selected cohorts and analysis of biological samples in monocytes. b Number of DEG across groups in monocytes (UP = upregulated genes, DOWN: downregulated genes) (FDR < 0.05). c Upset plot summarizing the number of differentially expressed genes at FDR < 0.05 in monocytes between manifesting and non-manifesting GBA carriers, PD and CTRL subjects in monocytes and the overlapping genes