Table 1.
Sex/age clinical onset (months) |
Age at diagnosis (months) | Auxological data | Neurological pattern | Clinical findings | MRI features | Pathology | Chemo-therapy | Surgery | RT | Outcome | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|
percentile | Z score | |||||||||||
M/18 | 26 |
W L W/L HC |
3rd 10th - |
-1.7 -1.2 -1.4 |
Irritability Hyperactivity Normal exam |
Ematiation Sleeping disorder |
suprasellar lesion (44 × 40x38 mm) hypothalamic-pituitary chiasmatic region, hydrocephalus |
Low-grade astrocytoma |
Carboplatin etoposide |
VP derivation |
no | alive |
F/8 | 14 |
W L W/L HC |
< 3rd 5th 75th |
-1.9 -1.6 -1.6 |
Normal exam Alert |
Pale skin emaciation |
suprasellar lesion (40 × 36x31 mm) hypothalamic-pituitary region, extended to 3rd ventricle |
Low-grade astrocytoma |
Carboplatin etoposide vinorelbin |
Resection | yes | died |
M/8 | 16 |
W L W/L HC |
10th >> 97th 90th |
-1.2 4.9 -5 |
Nistagmus Hyperactivity Normal exam |
Pale skin emaciation |
Multilobate pseudocystic suprasellar lesion (47 × 38x39 mm) hypothalamic-pituitary and chiasmatic region |
Pilomyxoid astrocytoma |
Carboplatin Etoposide bevacizumab irinotecan |
Debulking | no | alive |
MRI Magnetic resonance imaging, M male, F Female, W Weight, L Length, W/L Weight/Length, HC Head circumference, VP Ventriculo-peritoneal, RT Radiotherapy