Table 3.

Prevalence of auxological, clinical, pathologic features and therapy in children with DS

Auxological parameters (percentile)	%	Clinical features	%	Pathology	%	Therapy	%	Outcome	%
W < 5th	80	Nystagmus	43	Astrocytoma	83	Chemotherapy	49	Survivor	72.5
W/L or W/H or BMI < 5th	96	Vomiting	35	Craniopharyngioma	12.5	Radiotherapy	47	died	24.5
HC > 97th	25	Hyperactivity/happiness	26			Total resection	17
L or H < 5th	4	Visual loss	26			Partial resection	44
L or H > 97th	4	Strabismus	15
		Irritability	8
		Headache	8
		Neurodevelopment delay	7
		Anorexia	6
		Lethargy	5
		Papilledema	3
		Seizures	2

W Weight, L Length, H Height, W/L Weight/Length, W/H Weight/Height, BMI Body mass index, HC head circumference