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. 2022 Aug 17;23:789. doi: 10.1186/s12891-022-05731-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Targeted relationship between miR-215-5p and XIAP. A Potential targets of miR-215-5p were predicted by miRDB, TargetScan and Starbase. B Abnormal expressions of WNK1, RB1, XIAP, CTCF and RUNX1 in OP patients and healthy controls. C Correlation between miR-215-5p and XIAP in OP samples. D Expressions of WNK1, PB1, XIAP, CTCF and RUNX1 after transfection with miR-215-5p mimics in hBMSCs. E Dual-luciferase reporter assay confirmed the targeted relationship between miR-215-5p and XIAP. F qRT-PCR assay was conducted to examine the change of XIAP level before and after β-glycerophosphate treatment in hBMSCs. G Western blot assay was conducted to examine the change of XIAP level before and after β-glycerophosphate treatment in hBMSCs. H Effect of miR-215-5p transfection on XIAP level was determined by qRT-PCR analysis. I Effect of miR-215-5p transfection on XIAP level was determined by western blot analysis