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[Preprint]. 2022 Aug 11:2022.08.11.503614. [Version 1] doi: 10.1101/2022.08.11.503614

Table 2. Kinetics of excision of the Rp diastereomer of CMPαS and AMPαS by ExoN.

Data were fit to a single exponential to determine the observed rate of cleavage and half-life (t1/2).

NMP rate (min−1) t1/2 (min)
CMP 0.22 ± 0.010 3
CMPαS (Rp,Sp) 0.0016 ± 0.0003 350
AMP 0.13 ± 0.02 5
AMPαS (Rp) 0.0015 ± 0.0003 460