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[Preprint]. 2022 Aug 10:2022.08.05.22278483. [Version 1] doi: 10.1101/2022.08.05.22278483

Extended Data Fig. 2: SARS-CoV-2 R346S/Q493K and R346S/N440K/E484K pseudotype virus neutralization by C135-LS and C144-LS.

Extended Data Fig. 2:

a, Graphs show concentration-dependent neutralization curves for SARS-CoV-2 pseudoviruses by monoclonal antibodies. C144 (red), C135 (blue), and their equimolar combination (purple). b, Pre-pandemic plasma (squares) neutralization of WT or R346S/Q493K or R346S/N440K/E484K pseudoviruses in the absence or presence of 5 (purple dashed circles) or 100μg/ml (purple solid circles) of C135 and C14414. c-d, As in (b) but for convalescent plasma with intermediate (c, COV157)12 or strong (d, COV31)12 neutralizing activity. The horizontal lines in all panels indicate half-maximal neutralization.