FIGURE 1.

Sequence analysis of the nucleocapsid protein from the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) coronavirus. (a) Domain organization of N^{SARS‐CoV‐2} with glutamine residues highlighted by magenta bars underneath. (b and c) Prediction of prion‐like domains in the nucleocapsid protein of SARS‐CoV‐2 (b) and the Omicron variant (c) using the PLAAC algorithm. ⁹ , ¹⁰ Background and prion‐like domains are indicated by black and red lines, respectively. The gray rectangle highlights the region with the strongest differences. (d) N^{SARS‐CoV‐2} mutation and phosphorylation analysis. Amino acid frequency of mutations using 219,909 sequences from the China National Center for Bioinformatics. Mutations present in the Omicron variant of SARS‐CoV‐2 are shown in red. Phosphorylation sites are highlighted in green. Folded domains are highlighted by blue and green boxes.