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. 2022 Aug 4;10:969617. doi: 10.3389/fped.2022.969617

Table 1.

Sample characteristics.

MD a
Male n (%) 685 (59.4%) 0
Pregnancy n (%) 0
   Singleton 1099 (95.2%)
   Twins 53 (4.6%)
   Triplets 2 (0.2%)
Prenatal diagnosis of EA n (%) 287 (24.9%) 0
Weight at birth n (%) 1147 (99%) 7
mean ± SD 2,498 ± 713.1
Length at birth n (%) 865 (75%) 28
mean ± SD 46.7 ± 4.2 9
SGA b (weight or length) n (%) 118 (17%) 461
SGA for weight 159 (14.1%) 26
SGA for length 78 (9.2%) 304
Birth term (weeks of amenorrhea) n (%) 23
   ≥37 670 (59.2%)
   32–36 364 (32.2%)
    <32 97 (8.6%)
Total with associated abnormality n (%) 628 (54.4%) 0
   Neurologic n (%) 86 (7.5%) 0
   Renal n (%) 113 (9.8%) 0
   Cardiac n (%) 326 (28.2%) 0
   Limbs n (%) 103 (8.9%) 0
   Anorectal n (%) 109 (9.4%) 0
   Genital n (%) 71 (6.2%) 0
   Costovertebral n (%) 199 (17.2%) 0
VACTERL c or CHARGE d association n (%) 205 (17.8%) 0
Other syndromic association n (%) 150 (13%) 0
EAe type n (%) 18
   Type I 89 (7.8%)
   Type II 17 (1.5%)
   Type III 1002 (88.2%)
   Type IV 11 (1%)
   Type V 17 (1.5%)
Surgical treatment 38
   Esophageal anastomosis
n (%) 1090 (97.7%)
   Age at anastomosis (days) mean ± SD 14.5 ± 52 19
   Standard anastomosis n (%) 1056 (94.6%)
   Anastomosis with lengthening artifice n (%) 34 (3%)
   Colic transposition
n (%) 16 (1.4%)
   Age at colic transposition (days) mean ± SD 172.3 ± 113.8 0
   Gastric transposition
n (%) 10 (0.9%)
   Age at gastric transposition (days) mean +/ SD 157.2 ± 69.7 0
Anastomotic tension n (%) 323 (30.7%) 103
Timing of esophageal anastomosis n (%) 19
   Primary ( ≤ 15 days) 944 (88.1%)
   Delayed (> 15 days) 127 (11.9%)
Surgical approach n (%)
   Thoracotomy 960 (84.3%) 15
   Thoracoscopy 143 (12.9%) 45
   Cervicotomy 7 (0.6%) 27
Outcome at 1year of age n (%) 64
   Alive 965 (88%)
   Dead 86 (7.8%)
   Lost to follow-up 39 (3.6%)
a

Missing data,

b

Small for Gestational Age,

c

Vertebral defects, Anal atresia, Cardiac, Tracheoesophageal fistula, Renal and Limb,

d

Coloboma, Heart defect, Atresia choanae, Retarded growth and development, Genital hypoplasia, Ear anomalies,

e

Esophageal atresia.