Table 5.
Pharmacokinetic parameters of BER in Wistar rats after oral delivery of BER-SOL and BER-BLS.
Parameter | BER-SOL | BER-BLS |
---|---|---|
Cmax (ng/ml) | 95 ± 13.26 | 421 ± 24.73 |
Tmax (h) | 2 ± 0.45 | 2 ± 0.61 |
T1/2 (h) | 4.5 ± 0.71 | 4.5 ± 0.84 |
AUC0-t (ng. h/ml) | 382.75 ± 47.2 | 2441.1 ± 95.3 |
Mean residence time (h) | 5.27 ± 0.87 | 7.69 ± 0.59 |
Relative bioavailability (%) | – | 637.8 |