Table 1.
Demographic and clinical baseline characteristics of diagnosed NMIBC cases (n = 527) in a New Hampshire population-based study according to dietary instrument.a
| Characteristic | All (n = 527) |
Dietary Instrumentb | ||||
|---|---|---|---|---|---|---|
| Harvard FFQ (n = 242) |
NCI DHQ (n = 285) |
|||||
| n | (%) | n | (%) | n | (%) | |
| Age at Diagnosis, years c | ||||||
| Mean (SD) | 63.8 | (9.8) | 61.7 | (9.6) | 65.6 | (9.6) |
| <50 | 46 | (8.7) | 26 | (10.7) | 20 | (7.0) |
| 50–59 | 121 | (23.0) | 64 | (26.4) | 57 | (20.0) |
| 60–69 | 182 | (34.5) | 97 | (40.1) | 85 | (29.8) |
| 70–79 | 178 | (33.8) | 55 | (22.7) | 123 | (43.2) |
| Sex | ||||||
| Male | 388 | (73.6) | 177 | (73.1) | 211 | (74.0) |
| Female | 139 | (26.4) | 65 | (26.9) | 74 | (26.0) |
| Education | ||||||
| High School | 253 | (48.0) | 126 | (52.1) | 127 | (44.6) |
| College / Graduate / Professional | 271 | (51.4) | 113 | (46.7) | 158 | (55.4) |
| Unknownd | 3 | (0.6) | 3 | (1.2) | 0 | (0.0) |
| Smoking Status | ||||||
| Never | 82 | (15.6) | 39 | (16.1) | 43 | (15.1) |
| Former | 282 | (53.5) | 124 | (51.2) | 158 | (55.4) |
| Current | 158 | (30.0) | 79 | (32.6) | 79 | (27.7) |
| Unknownd | 5 | (0.9) | 0 | (0.0) | 5 | (1.8) |
| Body Mass Index, kg/m 2 | ||||||
| < 18.5 | 2 | (3.8) | 2 | (0.8) | 0 | (0.0) |
| 18.5–24.9 | 94 | (17.8) | 17 | (7.0) | 77 | (27.0) |
| 25.0–29.9 | 160 | (30.4) | 41 | (16.9) | 119 | (41.8) |
| > 30.0 | 103 | (19.5) | 18 | (7.4) | 85 | (29.8) |
| Unknown | 168 | (31.9) | 164 | (67.8) | 4 | (1.4) |
| AJCC Stage | ||||||
| 0is | 32 | (6.1) | 15 | (6.2) | 17 | (6.0) |
| 0a | 408 | (77.4) | 180 | (74.4) | 228 | (80.0) |
| I | 87 | (16.5) | 47 | (19.4) | 40 | (14.0) |
| Tumor Grade e | ||||||
| CIS | 33 | (6.3) | 15 | (6.2) | 18 | (6.3) |
| PUNLMP | 155 | (29.4) | 71 | (29.3) | 84 | (29.5) |
| Low Grade Carcinoma | 187 | (35.5) | 93 | (38.4) | 94 | (33.0) |
| High Grade Carcinoma | 152 | (28.8) | 63 | (26.0) | 89 | (31.2) |
| Treatment | ||||||
| None / TUR Onlyf | 429 | (81.4) | 200 | (82.6) | 229 | (80.4) |
| Systemic / Cystectomyg | 98 | (18.6) | 42 | (17.4) | 56 | (19.6) |
Abbreviations: AJCC, American Joint Committee on Cancer; CIS, carcinoma in-situ; DHQ, Diet History Questionnaire; FFQ, Food Frequency Questionnaire; NCI, National Cancer Institute; NMIBC, non-muscle invasive bladder cancer; PUNLMP, papillary urothelial neoplasm of low malignant potential; TUR, transurethral resection.
Percentages may not sum to 100% because of rounding.
The type of diet questionnaire differed by study phase. Harvard FFQ was administered July 1998 to December 2001 and NCI DHQ was administered January 2002 to July 2004.
Age range for Harvard FFQ was 32 to 74. Age range for NCI DHQ was 39 to 79.
Participants with unknown education and smoking status were excluded from survival analyses.
Determined using the World Health Organization/International Society of Urological Pathology classification.
Number of no treatment were as follows: Harvard FFQ, 7; NCI DHQ, 2. Number of TUR only treatment were as follows: Harvard FFQ, 193; NCI DHQ, 227.
Systemic treatment includes immunotherapy, intravesical chemotherapy, and/or radiation therapy.