Table 5.
Jejunal morphology and enterocyte proliferation in the crypt of pigs challenged with F18-positive Escherichia coli and fed diets supplemented with antibiotic (bacitracin methylene disalicylate) or Lactobacillus fermentate (LBF)
Item | Treatment1 | SEM | P-value | |||||
---|---|---|---|---|---|---|---|---|
NC | PC | AGP | PBT | NC vs. PC | PC vs. AGP | PC vs. PBT | ||
Villus height, µm | 369 | 309 | 377 | 362 | 22.64 | 0.068 | 0.038 | 0.102 |
Villus width, µm | 118 | 110 | 118 | 116 | 4.22 | 0.194 | 0.204 | 0.295 |
Crypt depth, µm | 213 | 230 | 219 | 248 | 10.29 | 0.259 | 0.475 | 0.227 |
VH:CD2 | 1.74 | 1.35 | 1.75 | 1.48 | 0.10 | 0.011 | 0.009 | 0.362 |
Ki67+3, % | 27.70 | 36.16 | 32.42 | 26.96 | 1.34 | <0.001 | 0.034 | <0.001 |
Treatments: NC, no-challenge/no-supplement; PC, E. coli challenge/no-supplement; AGP, E. coli challenge/bacitracin (30 g/t feed); and PBT, E. coli challenge/LBF (2 kg/t feed; LBiotix, Adare Biome, Houdan, France).
Villus height to crypt depth ratio.
Enterocyte proliferation in the crypt.