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. 2022 Jun 6;100(8):skac210. doi: 10.1093/jas/skac210

Table 5.

Jejunal morphology and enterocyte proliferation in the crypt of pigs challenged with F18-positive Escherichia coli and fed diets supplemented with antibiotic (bacitracin methylene disalicylate) or Lactobacillus fermentate (LBF)

Item Treatment1 SEM P-value
NC PC AGP PBT NC vs. PC PC vs. AGP PC vs. PBT
Villus height, µm 369 309 377 362 22.64 0.068 0.038 0.102
Villus width, µm 118 110 118 116 4.22 0.194 0.204 0.295
Crypt depth, µm 213 230 219 248 10.29 0.259 0.475 0.227
VH:CD2 1.74 1.35 1.75 1.48 0.10 0.011 0.009 0.362
Ki67+3, % 27.70 36.16 32.42 26.96 1.34 <0.001 0.034 <0.001

Treatments: NC, no-challenge/no-supplement; PC, E. coli challenge/no-supplement; AGP, E. coli challenge/bacitracin (30 g/t feed); and PBT, E. coli challenge/LBF (2 kg/t feed; LBiotix, Adare Biome, Houdan, France).

Villus height to crypt depth ratio.

Enterocyte proliferation in the crypt.