TABLE 4.
Effect of rpoS mutation on chronic lung infection caused by P. aeruginosa
| Parent or mutant | Initial inoculum (CFU/ml) | Quantitative bacteriology (CFU/ml) on daya:
|
Quantitative pathology (% damage) on day:
|
||
|---|---|---|---|---|---|
| 7 | 14 | 7b | 14 | ||
| RpoS+ (PAO1) | 3.5 × 104 | (4.4 ± 4.3) × 105 | (1.3 ± 1.2) × 105 | 18.5 ± 4.9 | 20.9 ± 8.8 |
| RpoS− (SS24) | 2.8 × 104 | (2.3 ± 2.2) × 106 | 1.2 × 106 ± 9.2 × 105 | 32.7 ± 3.8c | 56.2 ± 19.3c |
a
Values are means ± standard deviations.
b
Infiltration index.
c
Significantly different from RpoS+ value (P < 0.05) by Student’s t test.