TABLE 3.
mSEPT9 status by demographics of EOCRC cases and healthy controls.
| Variable | Healthy controls <50 years (N = 48) |
Healthy controls ≥50 years (N = 39) |
EOCRC (N = 27) |
|---|---|---|---|
| Age (n, %) | |||
| 26–29 | 0/1 (0.0) | – | 1/1 (100.0) |
| 30–34 | 0/1 (0.0) | – | 1/1 (100.0) |
| 35–39 | 0/4 (0.0) | – | 3/3 (100.0) |
| 40–44 | 1/20 (5.0) | – | 10/11 (90.9) |
| 45–49 | 1/23 (4.3) | – | 9/11 (81.8) |
| 50–54 | – | 3/17 (17.6) | – |
| 55–59 | – | 1/7 (14.3) | – |
| 60–64 | – | 1/8 (12.5) | – |
| 65–69 | – | 1/5 (20.0) | – |
| 70+ | – | 0/2 (0.0) | – |
| Race (n, %) | |||
| White | 1/9 (11.1) | 4/21 (19.0) | 19/22 (86.3) |
| Black | 1/23 (4.3) | 0/5 (0.0) | 2/2 (100.0) |
| Hispanic | 0/15 (0.0) | 2/7 (28.6) | 0/0 (0.0) |
| Asian | 0/1 (0.0) | 0/5 (0.0) | 1/1 (100.0) |
| Unknown | 0/0 (0.0) | 0/1 (0/0) | 2/2 (100.0) |
| Sex (n, %) | |||
| Female | 0/17 (0.0) | 2/14 (14.3) | 11/11 (100.0) |
| Male | 2/21 (9.5) | 4/25 (16.0) | 13/16 (81.3) |
| Cancer site (n, %) | |||
| Colon | – | – | 3/3 (100.0) |
| Rectum | – | – | 15/18 (83.3) |
| Unspecified colorectal site | – | – | 6/6 (100.0) |
| Stage (n, %) | |||
| I | – | – | 4/4 (100.0) |
| II | – | – | 1/1 (100.0) |
| III | – | – | 5/5 (100.0) |
| IV | – | – | 12/12 (100.0) |
| Unknown | – | – | 2/5 (40.0) |
| Tumor grade (n, %) | |||
| Low, low/intermediate | – | – | 10/11 (90.9) |
| Intermediate | – | – | 5/6 (83.3) |
| High | – | – | 6/7 (85.7) |
| Unknown | – | – | 3/3 (100.0) |
| Survival status, overall (n, %) | |||
| Alive | – | – | 18/21 (85.7) |
| Deceased | – | – | 6/6 (100.0) |
| Family history of cancer (n, %) | |||
| Yes | – | – | 19/21 (90.5) |
| No | – | – | 4/5 (80.0) |
| Unknown | – | – | 1/1 (100.0) |
| Family history of CRC (n, %) | |||
| Yes | – | – | 8/9 (88.9) |
| No | – | – | 15/17 (88.2) |
| Unknown | – | – | 1/1 (100.0) |
| History of IBD or chronic inflammation (n, %) | |||
| Yes | – | – | 5/5 (100.0) |
| No | – | – | 19/22 (86.4) |
Abbreviations: CRC, colorectal cancer; IBD, inflammatory bowel disease.