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. 2022 Jul 5;107(9):2439–2448. doi: 10.1210/clinem/dgac394

Figure 2.

Figure 2.

Histochemical and immunohistochemical staining for samples 1 and 2. (A-D) Low-magnification findings of histochemical and immunohistochemical staining for sample 1 (A, hematoxylin-eosin; B, CYP11B2; C, CYP11B1; D, CYP17A1). Dotted line indicates the outline of the adrenal gland and black arrows indicate APCCs. In panel C, the crosses indicate tissue folding. (E-H) High-magnification findings of histochemical and immunohistochemical staining for APCC of sample 1 (E, hematoxylin-eosin; F, CYP11B2; G, CYP11B1; H, CYP17A1). Dotted line indicates the outline of the APCC. In panel G, red arrowheads indicate CYP11B1-positive cells and blue arrowheads indicate CYP11B1-negative cells. (I-L) Low-magnification findings of histochemical and immunohistochemical staining for sample 2 (I, hematoxylin-eosin; J, CYP11B2; K, CYP11B1; L, CYP17A1). Dotted line indicates the outline of the adrenal gland and black arrowhead indicates APCC. (M-P) High-magnification findings of histochemical and immunohistochemical staining for APCC of sample 2 (M, hematoxylin-eosin; N, CYP11B2; O, CYP11B1; P, CYP17A1). Dotted line indicates the outline of the APCC.