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. 2022 Jun 13;107(9):2626–2635. doi: 10.1210/clinem/dgac365

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Published by Oxford University Press on behalf of the Endocrine Society 2022.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 3. — Distinct relative proportions of the classic and 11-oxygenated androgen pathways. Relative percentages for individual steroids, total classic pathway androgens (sum of androstenedione and testosterone), and total 11-oxygenated androgens (sum of 11OHA4, 11OHT, 11KA4, and 11KT) were significantly different among (A) healthy controls, (B) patients with lipodystrophy, and (C) patients with insulin receptoropathy (P < 0.05 for 1-way ANOVA). Abbreviations: 11dF, 11-deoxycortisol; 11OHA4, 11β-hydroxyandrostenedione; 11OHT, 11β-hydroxytestosterone; 11KA4, 11-ketoandrostenedione; 11KT, 11-ketotestosterone; A4, androstenedione; LD, lipodystrophy; T, testosterone.