Table 1.
Baseline characteristics of genotyped participants in the Chronic Renal Insufficiency Cohort Study
| Characteristic | Overall | White participants | Black participants | P |
|---|---|---|---|---|
| No. | 3027 | 1635 | 1392 | |
| Age, y | 58.5 (10.9) | 58.9 (11.0) | 58.1 (10.7) | .25 |
| Female, n (%) | 1358 (44.8) | 649 (39.7) | 709 (50.9) | < .01 |
| Body mass index | 32.3 (7.9) | 31.2 (7.3) | 33.6 (8.4) | < .01 |
| Prevalent diabetes, n (%) | 1427 (47.1) | 709 (43.4) | 718 (51.6) | < .01 |
| Prevalent CVD, n (%) | 1038 (34.3) | 503 (30.8) | 535 (38.4) | < .01 |
| eGFR, mL/min/1.73 m2 | 44.8 (14.8) | 45.4 (14.7) | 44.1 (14.9) | .12 |
| Systolic blood pressure, mm Hg | 127.8 (21.9) | 123.2 (19.4) | 133.1 (23.4) | < .01 |
| Diastolic blood pressure, mm Hg | 71.4 (12.9) | 69.3 (11.5) | 73.9 (14.1) | < .01 |
| Albumin-to-creatinine ratio, mg/g | 44.3 (7.9-391.4) | 29.6 (6.4-308.6) | 75.0 (11.3-513.7) | < .01 |
| Calcium, mg/dL | 9.2 (0.5) | 9.2 (0.5) | 9.2 (0.5) | .24 |
| Phosphate, mg/dL | 3.7 (0.7) | 3.6 (0.7) | 3.8 (0.7) | < .01 |
| Parathyroid hormone, pg/mL | 53 (34-87) | 45 (31-71) | 66 (40-111) | < .01 |
| FGF23, RU/mL | 144 (95-237) | 141 (94- 222) | 149 (96-253) | .02 |
Mean (SD), median (IQR), or n (%), as appropriate.
Abbreviations: CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; FGF23, fibroblast growth factor 23.
Bolded values are those reaching significance.