Figure 5.

Network analysis of master transcription factors and genes involved in the prolactin-associated metabolism at early postpartum. (A) Flow chart of the identification of co-expressed genes and master transcription factors (TFs) from prolactin-correlated metabolites using MetaBridge and iRegulon. (B) iRegulon analysis depicting the regulatory network between the master regulons associated with prolactin and their downstream target genes. Abbreviations: NES, normalized enrichment score; TF, transcription factor.