Cr-T cells were transient transfected with miR-NC, miR-27a, miR-27b with
vector control or Nrf2 ORF plasmid. (A) The expression of Nrf2 was
analyzed 72 h after transfection using immunoblotting assay. After 24 h post
transfection, cells were trypsinized and seed for cell proliferation assay using
MTT method (B), colony formation assay using soft agar
(C), transwell migration assay (D), and tube
formation assay (E). Quantitative results were shown using bar
graph from three independent experiments. * and #, p < 0.05 compared to
miR-NC group and miR-27a/b + Nrf2 group, respectively. ** and ##, p <
0.01 compared to miR-NC group and miR-27a/b + Nrf2 group, respectively.