Table 1. Demographics and Baseline Characteristics.
| UV-4 Dose Number in Cohort (N) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 3 mg (N = 6) | 10 mg (N = 6) | 30 mg (N = 6) | 90 mg (N = 6) | 180 mg (N = 6) | 360 mg (N = 6) | 720 mg (N = 6) | 1000 mg (N = 6) | All doses (N = 48) | Placebo (n = 16, [2 per cohort]) | |
| Cohort # | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | NA | NA |
| Sex | ||||||||||
| Male | 3 | 4 | 4 | 5 | 5 | 5 | 3 | 5 | 34 | 13 |
| Female | 3 | 2 | 2 | 1 | 1 | 1 | 3 | 1 | 14 | 3 |
| Race | ||||||||||
| White | 6 | 3 | 5 | 4 | 5 | 4 | 4 | 6 | 37 | 14 |
| African American or Black | 0 | 2 | 1 | 2 | 1 | 2 | 2 | 0 | 10 | 2 |
| American Indian or Alaska Native | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| Ethnicity | ||||||||||
| Hispanic or Latino | 1 | 1 | 0 | 1 | 3 | 0 | 0 | 1 | 7 | 2 |
| Not Hispanic or Latino | 5 | 5 | 6 | 5 | 3 | 6 | 6 | 5 | 41 | 14 |
| Age (years) | ||||||||||
| Mean | 25 | 27 | 27 | 28 | 28 | 29 | 25 | 27 | 27 | 28 |
| Minimum | 21 | 21 | 21 | 19 | 18 | 19 | 18 | 19 | 18 | 18 |
| Maximum | 35 | 41 | 32 | 43 | 43 | 44 | 42 | 38 | 44 | 41 |
| Weight (kg) | ||||||||||
| Mean | 82.9 | 79.6 | 80.8 | 75.9 | 84.0 | 80.1 | 74.1 | 75.0 | 79.1 | 76.2 |
| Minimum | 65.4 | 64.7 | 68.7 | 66.2 | 70.3 | 64.7 | 62.9 | 65.0 | 62.9 | 60.3 |
| Maximum | 99.0 | 102.7 | 95.7 | 88.9 | 94.4 | 95.0 | 95.2 | 82.0 | 102.7 | 95.1 |
| BMI (kg/m 2 ) | ||||||||||
| Mean | 27.44 | 26.88 | 26.44 | 24.76 | 27.05 | 26.13 | 24.86 | 24.93 | 26.06 | 24.89 |
| Minimum | 25.32 | 22.64 | 22.21 | 21.35 | 25.09 | 23.24 | 20.42 | 21.72 | 20.24 | 19.92 |
| Maximum | 28.6 | 29.13 | 28.36 | 29.2 | 29.79 | 28.59 | 28.58 | 26.04 | 29.79 | 28.27 |