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. 2022 Aug 4;10:923170. doi: 10.3389/fpubh.2022.923170

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Copyright © 2022 Feng, Dai, Liu, Li, Gou, Chen, Chen and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic profiles of plasma samples of NC, MT and MTS. (A) PCA score plots of the samples derived from the metabolite profiles in the ESI+ model, QC: quality control. (B) PCA score plots of the samples derived from the metabolite profiles in the ESI- model. (C) OPLS-DA score scatter plots of plasma samples of MTS vs. MT derived from the metabolite profiles in the ESI+ model. (D) OPLS-DA score scatter plots of plasma samples of MT vs. NC derived from the metabolite profiles in the ESI+ model. (E) OPLS-DA score scatter plots of plasma samples of MTS vs. NC derived from the metabolite profiles in the ESI+ model. (F) Permutation test of the OPLS-DA model for MTS vs. MT in the ESI+ model. N = 30 in each group. (A–F) were drawn by R version 4.0.2.