Table 2.
Secondary outcomes of RCTs included in meta-analysis.
| Outcomes | Studies include | RR or SMD 95% CI | p value for statistical significance | p value for statistical heterogeneity | I 2 test for heterogeneity |
|---|---|---|---|---|---|
| VAS/NRS scores at the PACU (at rest) | 9 | -1.86 (-2.59, -1.13) | <0.01 | <0.01 | 93% |
| VAS/NRS scores at the PACU (on movement) | 3 | -1.31 (-2.14, -0.48) | <0.01 | <0.01 | 82% |
| VAS/NRS scores at 2 h (at rest) | 7 | -1.73 (-2.70, -0.75) | <0.01 | <0.01 | 95% |
| VAS/NRS scores at 2 h (on movement) | 2 | -1.88 (-4.04, 0.27) | 0.09 | <0.01 | 95% |
| VAS/NRS scores at 4 h (at rest) | 8 | -1.38 (-2.15, 0.61) | <0.01 | <0.01 | 94% |
| VAS/NRS scores at 4 h (on movement) | 3 | -1.20 (-2.31, -0.09) | 0.03 | <0.01 | 91% |
| VAS/NRS scores at 6 h (at rest) | 8 | -2.26 (-3.54, -0.99) | <0.01 | <0.01 | 96% |
| VAS/NRS scores at 6 h (on movement) | 3 | -8.24 (-13.40, -3.08) | <0.01 | <0.01 | 98% |
| VAS/NRS scores at 12 h (at rest) | 9 | -0.69 (-1.14, -0.24) | <0.01 | <0.01 | 83% |
| VAS/NRS scores at 12 h (on movement) | 5 | -3.21 (-5.67, -0.75) | 0.02 | <0.01 | 94% |
| VAS/NRS scores at 24 h (at rest) | 14 | -0.52 (-0.75, -0.29) | <0.01 | <0.01 | 66% |
| VAS/NRS scores at 24 h (on movement) | 7 | -1.05 (-1.94, -0.17) | 0.02 | <0.01 | 94% |
| VAS/NRS scores at 48 h (at rest) | 7 | -0.33 (-0.61, -0.06) | 0.02 | 0.04 | 51% |
| VAS/NRS scores at 48 h (on movement) | 5 | -0.70 (-1.05, -0.35) | <0.01 | 0.07 | 53% |
| Time to first rescue analgesic | 9 | 4.87 (2.84, 6.90) | <0.01 | <0.01 | 98% |
| Intraoperative opioid consumption | 8 | -1.48 (-2.35, -0.6) | <0.01 | <0.01 | 94% |
| Number of patients rescue analgesia (n) | 10 | 0.32 (0.13, 0.80) | 0.02 | <0.01 | 97% |
| PONV (postoperative nausea and vomiting) | 13 | 0.35 (0.22, 0.55) | <0.01 | 0.27 | 18% |
| The length of hospitalize | 5 | -1.80 (-3.21, -0.39) | 0.01 | <0.01 | 97% |
| Patient satisfaction | 5 | 1.89 (1.03, 2.74) | <0.01 | <0.01 | 92% |