Table 1 . Results of blood gas analysis and wet to dry ratio 90 minutes after fluid resuscitation, and amount of bleeding.
| Item | SHAM | HS | HS+DEX | HS+DEX/MLA | HS+MLA | P |
|---|---|---|---|---|---|---|
| Body weight (g) | 407 ± 12 | 414 ± 17 | 409 ± 15 | 406 ± 15 | 412 ± 14 | 0.977 |
| Shed blood volume (ml) | 9.5 ± 0.3 | 9.2 ± 0.5 | 9.4 ± 0.5 | 9.5 ± 0.6 | 0.958 | |
| PaO2 (mmHg) | 89.4 ± 7.2 | 88.9 ± 9.5 | 96.7 ± 5.6 | 90.5 ± 10.2 | 92.3 ± 7.2 | 0.259 |
| PaCO2 (mmHg) | 37.3 ± 4.0 | 34.5 ± 3.5 | 30.4 ± 2.3 | 31.9 ± 5.6 | 34.5 ± 3.7 | 0.333 |
| Hemoglobin (g/dL) | 13.4 ± 0.3 | 10.8 ± 0.9a,b | 8.8 ± 0.7a | 10.4 ± 1.6a,c | 10.8 ± 0.8a,c | <0.001 |
| wet to dry ratio | 4.7 ± 0.2 | 5.4 ± 0.4a,b | 4.7 ± 0.3 | 5.2 ± 0.2c | 5.3 ± 0.3a,c | <0.001 |
Data are expressed as mean±standard deviation. P values were calculated from ANOVA followed by the Holm post hoc test. SHAM no shock, HS hemorrhagic shock, HS+DEX hemorrhagic shock with dexmedetomidine, HS+DEX/MLA hemorrhagic shock with dexmedetomidine and methyllycaconitine citrate, HS+MLA hemorrhagic shock with methyllycaconitine citrate. aP<0.01 vs. SHAM. bP<0.01 vs. HS+DEX. cP<0.05 vs. HS+DEX.