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. 2022 Aug 5;109(8):1388–1404. doi: 10.1016/j.ajhg.2022.07.002

Figure 4.

Figure 4

Heritability and correlation analysis reveal evidence for shared genetic architecture for expression in LCLs

(A) The scatter plot for the SNP heritability (cis-hg2) of lymphoblastoid cell line (LCL) gene expression for African American (AA) and European American (EA) ancestry in the GENOA study.

(B and C) The scatterplots where the y axis is a squared correlation (r2) between measured LCL gene expression in GEUVADIS and predicted by eQTL panels from GENOA, and the x axis is cis-hg2. Each point represents a gene. The blue line is estimated using ordinary linear regression.