. 2021 Jul 5;47(9):3101–3117. doi: 10.1007/s00261-021-03190-w

Table 3.

For different histopathological grading of PDAC mean/median, BF values are reported in (mL/100 g/min), BV is reported in (mL/100 g), and PS is reported in (mL/100 g/min)

Study	Histopathological grade
Kovac et al. [24]	BF: 17.45 ± 4.1^a BV: 2.66 ± 1.0^a		BF: 28.5 ± 7.7^a BV: 5.5 ± 1.4^a
D'Onofrio et al. [40]	BF: 5.9^b BV: 11.3^{a, b}		BF: 8.9^b BV: 19^{a, b}
Schneeweiβ et al. [39] (Max Slope + Patlak)	BF: 21.9 ± 10.4 BV: 5.5 ± 4.5 PS: 11.5 ± 6.4	BF: 21.9 ± 10.4 BV: 5.5 ± 4.5 PS: 21.0 ± 10.2	BF: 20.6 ± 8.6 BV:8.9 ± 11.3 PS:19.3 ± 4.5
Schneeweiβ et al. [39] (Deconvolution)	BF: 35.6 ± 13.9 BV: 6.1 ± 3.9 PS: 11.9 ± 7.1	BF: 37.7 ± 16.6 BV: 7.9 ± 5.5 PS: 13.7 ± 8.8	BF: 33.5 ± 10.3 BV: 6.4 ± 1.3 PS: 11.5 ± 6.4

Study

Histopathological grade

High

Intermediate

Low grade

Kovac et al. [24]

BF: 17.45 ± 4.1^a

BV: 2.66 ± 1.0^a

BF: 28.5 ± 7.7^a

BV: 5.5 ± 1.4^a

D'Onofrio et al. [40]

BF: 5.9^b

BV: 11.3^{a, b}

BF: 8.9^b

BV: 19^{a, b}

Schneeweiβ et al. [39]

(Max Slope + Patlak)

BF: 21.9 ± 10.4

BV: 5.5 ± 4.5

PS: 11.5 ± 6.4

BF: 21.9 ± 10.4

BV: 5.5 ± 4.5

PS: 21.0 ± 10.2

BF: 20.6 ± 8.6

BV:8.9 ± 11.3

PS:19.3 ± 4.5

Schneeweiβ et al. [39]

(Deconvolution)

BF: 35.6 ± 13.9

BV: 6.1 ± 3.9

PS: 11.9 ± 7.1

BF: 37.7 ± 16.6

BV: 7.9 ± 5.5

PS: 13.7 ± 8.8

BF: 33.5 ± 10.3

BV: 6.4 ± 1.3

PS: 11.5 ± 6.4

Kovac and D'Onofrio classified both moderate- and well-differentiated lesions as low grade

^aSignificant differences between pathological grading groups. Grade was high (poorly differentiated), intermediate (moderately differentiated), or low (well differentiated)

^bMedian values, rest of the table report mean values