Table 2.
Mean inhibition rates per time sampling1 and characteristic of HCP
| First sampling | Second sampling | Third sampling | |||||
|---|---|---|---|---|---|---|---|
| n | mean inhibition (%) | n | mean inhibition (%) | n | mean inhibition (%) | p-value | |
| SARS-CoV-2 infection2 | |||||||
| no | 507 | 86.33 (13.96) | 473 | 73.38 (19.27) | 212 | 61.18 (21.62) | < 0.001 |
| yes | 37 | 95.41 (6.50) | 37 | 92.29 (10.98) | 18 | 93.62 (13.04) | |
| Gender | |||||||
| male | 163 | 83.56 (16.30) | 139 | 72.08 (20.17) | 55 | 55.91(22.98) | 0.033 |
| female | 344 | 87.64 (12.51) | 334 | 73.92 (18.88) | 157 | 63.02 (20.88) | |
| Age (years) | |||||||
| <40 | 133 | 91.16 (10.96) | 115 | 78.60 (18.29) | 39 | 70.02 (21.54) | < 0.001 |
| 40–59 | 306 | 85.16 (13.53) | 297 | 73.31 (18.63) | 149 | 60.83 (21.01) | |
| ≥60 | 55 | 76.93 (17.20) | 53 | 63.37 (20.80) | 21 | 48.49 (19.99) | |
| Mild adverse events3 | |||||||
| yes | 163 | 88.56 (12.75) | 208 | 75.16 (18.40) | 91 | 63.18 (21.59) | 0.023 |
| no | 175 | 85.30 (14.80) | 179 | 71.43 (19.63) | 89 | 59.27 (21.54) | |
| Comorbidities | |||||||
| yes | 76 | 81.52 (17.55) | 89 | 69.81 (19.30) | 44 | 56.57 (22.11) | < 0.001 |
| no | 255 | 88.30 (12.41) | 291 | 74.43 (18.94) | 134 | 63.0 (21.17) | |
| Immunosuppressive drugs | |||||||
| yes | 10 | 60.61 (25.79) | 13 | 50.81 (22.41) | 7 | 42.56 (20.23) | < 0.001 |
| no | 328 | 87.68 (12.64) | 374 | 73.87 (18.80) | 174 | 62.07 (21.13) | |
| BMI | |||||||
| < 20 | 18 | 87.29 (12.60) | 22 | 73.46 (18.74) | 13 | 60.43 (22.21) | 0.780 |
| 20–25 | 122 | 86.84 (12.96) | 139 | 73.39 (18.35) | 75 | 60.99 (20.48) | |
| 25,1–30 | 118 | 86.44 (14.95) | 128 | 75.32 (17.97) | 51 | 59.14 (23.54) | |
| > 30 | 52 | 87.39 (15.49) | 65 | 70.22 (20.70) | 22 | 63.18 (21.92) | |
| Smoking | |||||||
| yes | 114 | 80.93 (17.32) | 123 | 65.82 (21.04) | 63 | 51.06 (21.80) | < 0.001 |
| no | 224 | 89.84 (10.64) | 264 | 76.96 (16.95) | 117 | 66.67 (19.43) | |
| Regular physical excersice | |||||||
| yes | 74 | 86.89 (13.12) | 75 | 72.86 (16.71) | 47 | 60.28 (20.13) | 0.458 |
| no | 266 | 86.90 (14.12) | 312 | 73.57 (19.58) | 134 | 61.69 (22.10) | |
n: number of samples; HCP: healthcare personnel; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; BMI: body mass index.
1
after the 2nd vaccine dose
2
92 samples collected from 72 HCP with SARS-CoV-2 infection
3
after vaccination