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. 2022 Aug 18;8(1):65. doi: 10.1038/s41537-022-00273-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Scatter box plots for 10 significantly differential BAs in the discovery set. The comparisons between the two groups were conducted by the Mann–Whitney U tests, excluding outliers and correcting with FDR. *q < 0.05; **q < 0.01. Scatter box plots for the ratio of CA to CDCA (B), total BAs (TBAs) (C), and total unconjugated BAs (D). The comparisons between the two groups were conducted by the Mann–Whitney U tests, excluding outliers. *p < 0.05; ***p < 0.001. Center lines of box plots show median values, box hinges indicate 1st and 3rd quartiles, and whisker represent the furthest data points within 1.5 interquartile ranges of the hinges.