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. 2022 Aug 18;13:4477. doi: 10.1038/s41467-022-32015-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A BMI-related bacterial genera, which were selected and ranked according to R² score from single regression analysis (P < 0.05) among 16 genera that were identified through multiple-regression analysis by forward selection (Supplementary Table 3) by using the data of the 217 participants (Supplementary Table 1). B T2DM-related bacterial genera, which are selected and ranked according to R² score from single regression analysis (P < 0.05) among 22 genera that were identified through multiple logistic regression analysis by forward selection (Supplementary Table 4) by using the data of 192 participants (comprising 147 nonDM subjects and 45 T2DM patients and excluding 25 patients with Type 1 diabetes) (Supplementary Table 1). C Intestinal genera associated with both BMI and T2DM. D Odds ratios for Blautia abundance in the development of obesity (BMI ≥ 25) and T2DM. E Estimation of Blautia species according to BlastN analysis of representative OTU sequences.