Table 1.
Baseline, operative and histopathological parameters of patients who underwent parenchyma- sparing resections versus oncologic resections
| Baseline and Operative Parameters | ||||
|---|---|---|---|---|
| Total cohort | PSR | Oncologic resection | ||
| Total n | 810 (100.0) | 221 (27.3) | 589 (72.7) | |
| Parameter | n(%)/mean (SE) | n(%)/mean (SE) | n(%)/mean (SE) | p-value |
| Age in years | 59 (0.90) | 55 (0.95) | 53 (0.91) | 0.731 |
| Gender | ||||
| Female | 392 (48.4) | 110 (49.8) | 282 (47.9) | 0.618 |
| ASA score | ||||
| III-IV | 352 (43.4) | 93 (43.9) | 259 (44.0) | 0.999 |
| BMI in kg/m2 | 30.4 (1.13) | 30.3 (0.7) | 30.5 (1.22) | 0.208 |
| Minimal invasive procedures | 296 (36.5) | 72 (32.6) | 224 (38.0) | 0.29 |
| Blood loss (ml) | 374.3 (29.3) | 209.1 (24.8) | 411.2 (30.3) | <0.001 |
| Operative time(min) | 259.0 (7.2) | 180 (8.3) | 272.6 (6.3) | <0.001 |
| Histopathological parameters | ||||
| WHO Grading | ||||
| G1 | 626 (77.3) | 192 (86.8) | 434 (73.7) | |
| G2 | 168 (20.8) | 28 (12.7) | 140 (23.8) | |
| G3 | 16 (1.9) | 1 (0.4) | 15 (2.5) | <0.001 |
| Ki-67 Index | ||||
| >3 | 195 (24.1) | 29 (13.1) | 166 (28.5) | 0.002 |
| Vascular invasion | 155 (19.3) | 28 (13.9) | 127 (21.6) | 0.011 |
| Perineural invasion | 168 (20.7) | 18 (8.9) | 150 (25.5) | <0.001 |
| Lymph nodes harvested | ||||
| Yes | 674 (83.3) | 111 (40.2) | 550 (93.4) | <0.001 |
| Number of lymph nodes harvested | 11.9 (0.3) | 1.4 (0.2) | 14.0 (0.4) | <0.001 |
| Lymph nodes positive | 0.9 (0.07) | 0.9 (0.09) | 1.59 (0.07) | 0.127 |
| Positive nodal status | 128 (15.8) | 15 (18.5) | 113 (19.2) | 0.988 |
| T stage (AJCC 8th ed.) | ||||
| T3–4 | 126 (15.4) | 19 (8.6) | 107 (18.1) | 0.049 |
| R status | ||||
| R+ | 95 (11.7) | 58 (26.2) | 37 (6.3) | <0.001 |
PSR: Parenchyma-sparing resection; ASA: American Society of Anesthesiologists; BMI: Body mass index