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. 2022 Jul 7;121(15):2895–2905. doi: 10.1016/j.bpj.2022.07.001

Figure 2.

Figure 2

Visualization of single trajectories in the fast (A) and slow (B) spreading regimes. In the former case, the spreading occurs fast and independently of chromatin configuration, while in the latter case, the pattern of spreading may be determined by the dynamic rearrangement of the chromatin, as explained in the main text. The kymographs show the epigenetic identity of each nucleosome (marked/M/red, unmarked/U/yellow, NS/green) for a single trajectory, in both (A) and (B). Three distinct simulation time steps are chosen, marked with a symbol on the kymograph, and we extract polymer conformations with epigenetic identities of the nucleosomes to graphically represent them. For clarity, the size of the NS is enhanced. Accompanying Videos S1 and S2 are available online. To see this figure in color, go online.