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. 2022 Aug 18;12:14070. doi: 10.1038/s41598-022-17111-4

Table 2.

Number of differentially expressed (up-and downregulated) genes in the different M-stages in comparison to healthy skin tissue.

n genes upregulated (Padj ≤ 0.05; FC ≥ 2) n genes downregulated (Padj ≤ 0.05; FC ≤ − 2)
M1 1059 1380
M2 1041 1345
M3 917 1148
M4 978 1423
M4.1 1063 1398

The fold change (FC) and adjusted p-value (Padj) threshold are shown between brackets. The fold change threshold is set at ≥ 2 for upregulated genes and ≤ − 2 for downregulated genes.