. Author manuscript; available in PMC: 2023 Nov 1.

Published in final edited form as: Semin Cancer Biol. 2022 Feb 19;86(Pt 1):80–100. doi: 10.1016/j.semcancer.2022.02.020

Table 1.

Popular modes of classifying extracellular vesicles (EVs)

A. Based on size of EVs
Type of EV	Size (Diameter in nm)	Morphology	References
Small EVs	< 100 nm < 200 nm	Spherical	[15]
Medium/large EVs	> 200 nm	Spherical	[15]
B. Based on the origin of EVs
Type of EV	Production Mode	Morphology	References
Apoptotic bodies	Blebbing	Heterogeneous	[190]
Microvesicles	Outward budding and shedding	Spherical	[190]
Exosomes	MVBs fusion with plasma membrane	Spherical or cup shaped with bilayer membrane	[191]
Exomeres	MVBs fusion with plasma membrane	Non-membranous, spherical	[192]
Migrasomes	Formed during cell migration	Pomegranate-like structures-oval shaped	[193]
Oncosomes	vesicle budding and membrane scission	Spherical	[194]