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. 2022 Aug 5;10:887076. doi: 10.3389/fcell.2022.887076

FIGURE 2.

FIGURE 2

Prognosis construction model based on the neurotransmitter receptor-related genes in the ICGC-LIRI-JP dataset. (A) Univariable cox survival analysis of the 115 neurotransmitter receptor-related genes, and nine genes were significantly correlated with the prognosis of patients with HCC. (B,C) LASSO regression model construction based on the nine predictive genes in the ICGC-LIRI-JP dataset, and 8 genes were successfully included in the model. (D) Distribution of the risk scores, survival status, and expression of the eight critically predictive genes. (E) The Kaplan–Meier analysis of overall survival in the high-risk scores group and low-risk scores group. (F) The ROC analysis to evaluate the predictive of risk scores efficiency. CI, confidence interval; HCC, hepatocellular carcinoma; ROC, receiver operator characteristic.