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. 2022 Aug 5;10:887076. doi: 10.3389/fcell.2022.887076

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Copyright © 2022 Wang, Li, Shi, Luo, Zhang, Pan, Wu, Tian and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Risk score model validation, DEGs screen and potential pathways enrichments using nine HCC samples. (A) Correlations among risk score and clinical characteristics. (B) PCA and t-SNE plot of nine HCC samples. (C) Volcano plot of DEGs. (D) Heat map of DEGs between two groups. (E) Top ten enriched GO-BP and circle plots for up-regulated DEGs. (F) Top ten enriched GO-BP and circle plots for downregulated DEGs. DEGs, differentially expressed genes; GO, gene ontology; BP, biological process; HCC, hepatocellular carcinoma; PCA, principal component analysis; t-SNE, t-distributed Stochastic Neighbor Embedding; TNM, clinicopathological stage; PVTT, portal vein tumor thrombus.