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. 2022 Aug 5;9:880763. doi: 10.3389/fmed.2022.880763

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Copyright © 2022 Sun, Chen, Chai, Niu, Dobbins, Nichols and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluate the risk of thrombosis after AAV8/hFVa treatment by fibrinolysis on ROTEM. Fibrinolysis analysis using whole blood collected from the inferior vena cava at the end of experiments was performed on ROTEM for mice (Figure 6).