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. 2022 Aug 5;13:917584. doi: 10.3389/fgene.2022.917584

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Copyright © 2022 Xu, Zhao, Huang, Zhang, Yin, Liu, Wu, Weng and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in clinical features and efficacy of immunotherapy among patients with different risk scores (A–D) Risk score was correlated with T, N, Stage and Grade; (E) The expression of prognostic related genes in clinical factors and different risk groups; (F) The violin chart of patients’ response to immunotherapy in high and low-risk groups. Blue represented low-risk group, red represented high-risk group; (G) Expression of immune checkpoints in two risk subgroups. * represented p < 0.05, ** represented p < 0.01, and *** P represented <0.001.